Article  |   October 2011
Children With 7q11.23 Duplication Syndrome: Speech, Language, Cognitive, and Behavioral Characteristics and Their Implications for Intervention
Author Affiliations & Notes
  • Shelley L. Velleman
    University of Vermont, Burlington, VT
  • Carolyn B. Mervis
    University of Louisville, Louisville, KY
  • © 2011 American Speech-Language-Hearing AssociationAmerican Speech-Language-Hearing Association
Article Information
Speech, Voice & Prosodic Disorders / Speech, Voice & Prosody
Article   |   October 2011
Children With 7q11.23 Duplication Syndrome: Speech, Language, Cognitive, and Behavioral Characteristics and Their Implications for Intervention
SIG 1 Perspectives on Language Learning and Education, October 2011, Vol. 18, 108-116. doi:10.1044/lle18.3.108
SIG 1 Perspectives on Language Learning and Education, October 2011, Vol. 18, 108-116. doi:10.1044/lle18.3.108

7q11.23 duplication syndrome is a recently documented genetic disorder associated with severe speech delay, language delay, a characteristic facies, hypotonia, developmental delay, and social anxiety. Children with this syndrome demonstrate developmentally appropriate nonverbal pragmatic abilities in socially comfortable situations. Motor speech disorder (childhood apraxia of speech and/or dysarthria), oral apraxia, and/or phonological disorder, or symptoms of these disorders, are common, as are characteristics consistent with expressive language disorder. Intensive speech/language therapy is critical for maximizing long-term outcomes.

Acknowledgments
Preparation of this manuscript was supported by grants #R01 NS35102 from the National Institute of Neurological Disorders and Stroke and #R37 HD29957 from the National Institute of Child Health and Human Development (C. B. Mervis, PI).
Become a SIG Affiliate
Pay Per View
Entire SIG 1 Perspectives on Language Learning and Education content & archive
24-hour access
This Issue
24-hour access
This Article
24-hour access